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Beneficial effects of long-term triiodothyronine (T 3) infusion in patients with advanced heart failure and low T 3 syndrome.
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Long-term lithium treatment may lead to goiter in about 50% of cases and may induce subclinical (34%) or overt (15%) hypothyroidism ().
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Monitor for changes in prothrombin time and anticoagulant effects if levothyroxine is initiated, discontinued or dose changed.
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Thr92AlaD2 polymorphism has resulted in some studies in tissue T 3 insufficiency ().
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Effects of growth hormone therapy on thyroid function of growth hormone-deficient adults with and without concomitant thyroxine-substituted central hypothyroidism.
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In a prospective study on 119 consective pregnancies, about 49% of women on l-T 4 replacement therapy had serum TSH outside the reference range (30% had elevated TSH concentrations, and 20% had low TSH concentrations) during the first trimester of pregnancy ().
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New data suggesting that combined therapy with T 3 and T 4 could be indicated in some patients with hypothyroidism are assessed, and the indications for TSH suppression with l-T 4 in patients with euthyroid multinodular goiter and in those with differentiated thyroid cancer are reviewed.
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