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RCT) demonstrated that patients are unable to detect differences in the symptoms associated with hypothyroidism when the LT 4 dose is changed by approximately 20%.

Los hallazgos fueron publicados en la edicin del 22 de octubre de Archives of Internal Medicine.

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We conclude that in patients with hypothyroidism, partial substitution of triiodothyronine for thyroxine may have more salutary effects on the brain and perhaps other tissues than those of an equivalent amount of thyroxine, as determined by their effects on thyrotropin secretion.

The study findings are published in the Jan. 27 issue of the journal Nature.

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