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Amisulpride versus risperidone in the treatment of schizophrenic patients: a double-blind pilot study in Taiwan.

The benefits of natural treatment methods is that they get to the underlying cause of the problem, rather than just managing the symptoms.

The low-dose data were mainly from Asian clinical trials, whereas the high-dose data were obtained from Western clinical trials.

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Patients involved in the brain imaging studies described above will also have information on drug dosage, levels of drug in the bloodstream and clinical response collected as drug dose is increased over a 10 week period.

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There have been trials on drugs with anti-inflammatory activity, based on the premise that inflammation might play a role in the pathology of schizophrenia.

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The development of atypical antipsychotic drugs represents a significant advance in the treatment of schizophrenia.

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Second-generation (atypical) antipsychotic drugs have been considered to be at least as effective as conventional antipsychotic agents such as haloperidol, with a lower risk of most adverse effects, and are used as first-line pharmacologic treatments for patients with dementia.

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Consequently, the risk for treatment-emergent adverse events is significantly increased (Table 2).

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The incidence of TD is as high as 70% in elderly patients treated with antipsychotic agents.

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Preliminary data suggest that low doses of atypical antipsychotic medications augmented by psychosocial treatments may delay the onset of psychosis in some individuals.

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Because early treatment choice is critical in first episode schizophrenia-spectrum disorders (FES), this meta-analysis compared efficacy and tolerability of individual second-generation antipsychotics (SGAs) with first-generation antipsychotics (FGAs) in FES.

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There were no significant differences between aripiprazole and placebo in mean change from baseline in the extrapyramidal symptom rating scales.

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IM medication, such as every 2-4 weeks, is preferred by some patients since it obviates the need to take medication every day.

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As indicated above, the route of administration may depend on the condition being treated.

Findings regarding olanzapine have since been corroborated in a similarly designed study using matched normal controls.

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Treatment was also effective in secondarily improving women's marital satisfaction, reducing husbands' levels of psychological distress and depression-specific burden, and improving both partners' understanding and acceptance of depression.

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Pointing to the tendency to misinterpret statistical probability (P) values, the article discusses the concepts of statistical power and effect size.

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Based on currently available data, the prescription of topiramate in addition to clozapine appears doubtful: while the substance showed only meagre effects regarding clinical symptomatology and reduction of body weight, it harbors the important risk of cognitive impairment (Muscatello et al.

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In a study by Grant et al, low-functioning patients with prominent negative symptoms were assigned to either recovery-oriented cognitive-behavioral therapy plus standard treatment or standard treatment; after 18 months, the authors found that both negative and positive symptoms had decreased in the group receiving the add-on cognitive therapy.

This paper reports the receptor binding profiles and the main mechanism of action of these drugs, together with their main use in psychiatry and the possible adverse events in elderly people.

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The receptor-binding profiles that correlate with antipsychotic-associated dyslipidemia are not well understood; however, emerging evidence suggests that PPAR agonism may convey a therapeutic benefit.

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Antidepressants and anti-anxiety drugs may also play an important role in treating the patient with schizophrenia, particularly given the role of depression in the high rates of suicide among these patients.

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